Fig. 5

Tanshinone IIA (TIIA) + cyclosporine A (CsA) preserved mitochondrial biogenesis and dynamics in renal renal ischemia-reperfusion (IR)-induced myocardial injury. The expression of PGC-1α, Nrf1, and Tfam in mRNA (a) and protein (b) level. The expression of Mfn1, Mfn2, and Drp1 in mRNA and protein level level. *p < 0.05 versus sham group, ^#p < 0.05 versus IR (obese) group, ^△p < 0.05 versus TIIA group, ^▲p < 0.05 versus CsA group