Fig. 2
From: In vitro inhibitory effect of obtusofolin on the activity of CYP3A4, 2C9, and 2E1

Lineweaver-Burk plots (A) and the secondary plot for Ki (B) of the inhibition of obtusofolin on CYP2C9 in pooled HLMs. Data were obtained from the incubation with 5–20 μM diclofenac in the presence of 0, 2, 5, 10, and 20 μM obtusofolin